Two Cases of Aspergillus Endocarditis in Patients with Acute Lymphoblastic Leukemia / 감염과화학요법
Infection and Chemotherapy
; : 332-336, 2003.
Article
de Ko
| WPRIM
| ID: wpr-721446
Bibliothèque responsable:
WPRO
ABSTRACT
Although Aspergillus endocarditis has rarely been reported, it can cause fatal complications in hematologic malignancy patients and allogeneic stem cell transplant recipients. We experienced two cases of aspergillus endocarditis developed in acute lymphoblastic leukemia patients. Case; A 19-year-old patient developed Aspergillus endocarditis after allogenic hemopoietic stem cell transplantation. He was treated with surgical intervention and liposomal amphotericin B. He died of recurred Aspergillus endocarditis and cerebral hemorrhage probably related with aspergillosis of central nervous system. Case 2; A 23-year-old patient developed invasive Aspergillus endocarditis after induction chemotherapy. Aspergillus endocarditis was successfully treated by surgical intervention and amphotericin B. He died of refractory neutropenic fever and sepsis after the third relapse of leukemia and repetitive chemotherapy. He probably had invasive pulmonary aspergillosis without evidence of endocarditis recurrence. Because the mortality of Aspergillus endocarditis is very high, early diagnosis and surgical intervention are very important for better outcome.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Ostéomyélite
/
Aspergillose
/
Aspergillus
/
Récidive
/
Cellules souches
/
Transplantation
/
Leucémies
/
Système nerveux central
/
Hémorragie cérébrale
/
Amphotéricine B
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Infection and Chemotherapy
Année:
2003
Type:
Article