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Thiamine Deficiency in a Child with Short Bowel Syndrome and Review / 대한소아소화기영양학회지
Article de En | WPRIM | ID: wpr-760866
Bibliothèque responsable: WPRO
ABSTRACT
Thiamine (vitamin B₁) is a water-soluble vitamin that is not endogenously synthesized in humans. It is absorbed by the small intestine, where it is activated. Its active form acts as a coenzyme in many energy pathways. We report a rare case of thiamine deficiency in a 3.5-year old boy with short bowel syndrome secondary to extensive bowel resection due to necrotizing enterocolitis during his neonatal age. The patient was parenteral nutrition-dependent since birth and had suffered from recurrent central catheter-related bloodstream infections. He developed confusion with disorientation and unsteady gait as well as profound strabismus due to bilateral paresis of the abductor muscle. Based on these and a very low thiamine level he was diagnosed and treated for Wernicke encephalopathy due to incomplete thiamine acquisition despite adequate administration. He fully recovered after thiamine administration. After 1999 eight more cases have been reported in the PubMed mostly of iatrogenic origin.
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Texte intégral: 1 Indice: WPRIM Sujet Principal: Parésie / Syndrome de l'intestin court / Thiamine / Carence en thiamine / Vitamines / Encéphalopathie de Gayet-Wernicke / Strabisme / Nutrition parentérale totale / Entérocolite nécrosante / Troubles neurologiques de la marche Limites du sujet: Child / Humans / Male langue: En Texte intégral: Pediatric Gastroenterology, Hepatology & Nutrition Année: 2019 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Parésie / Syndrome de l'intestin court / Thiamine / Carence en thiamine / Vitamines / Encéphalopathie de Gayet-Wernicke / Strabisme / Nutrition parentérale totale / Entérocolite nécrosante / Troubles neurologiques de la marche Limites du sujet: Child / Humans / Male langue: En Texte intégral: Pediatric Gastroenterology, Hepatology & Nutrition Année: 2019 Type: Article