Report of the Korean Association of Lung Cancer Registry (KALC-R), 2014 / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
; : 1400-1410, 2019.
Article
Dans En
| WPRIM
| ID: wpr-763220
Responsable en Bibliothèque :
WPRO
ABSTRACT
PURPOSE:
The aim of this study was to investigate epidemiology, clinical characteristics and sex differences of patients with lung cancer using nationwide registry in Korea. MATERIALS ANDMETHODS:
The Korean Association for Lung Cancer developed a registry in cooperation with the Korean Central Cancer Registry, and surveyed about 10% of lung cancer cases. For this first survey of cases diagnosed in 2014, cases were selected through a systematic sampling method.RESULTS:
Total 2,621 lung cancer patients were surveyed, and the median patient age was 70 years. During the study period, adenocarcinoma was the most frequent histologic type, the proportion of female patients was 28.4%, and women had a better prognosis (median survival, not reached vs. 13 months; p<0.001) than did men for non-small cell lung cancer. The proportion of never-smokers was 36.4%, and never-smoking was more prevalent in women than in men (87.5 vs. 16.0%, p<0.001). Epidermal growth factor receptor (EGFR) mutations were found in 36.8% of stage IV adenocarcinoma patients, and higher in female compared to male patients (51.2 vs. 26.6%, p<0.001). In addition, patients with EGFR mutation showed better survival (median survival, 18 vs. 8 months; p<0.001) than patients without EGFR mutation in these patients.CONCLUSION:
This is the first survey to gather unbiased nationwide lung cancer statistics in Korea. More than one-third of lung cancer patients had no smoking history. Female had a high proportion of non-smoker, more adenocarcinoma with EGFR mutation and generally better prognosis than male.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pronostic
/
Fumée
/
Adénocarcinome
/
Fumer
/
Épidémiologie
/
Caractères sexuels
/
Carcinome pulmonaire non à petites cellules
/
Récepteurs ErbB
/
Corée
/
Poumon
Type d'étude:
Prognostic_studies
Limites du sujet:
Female
/
Humans
/
Male
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Cancer Research and Treatment
Année:
2019
Type:
Article