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Antimicrobial activity of Garcinia mangostana L. ethanol extract against Cutibacterium acnes and Staphylococcus aureus
Article de Ko | WPRIM | ID: wpr-764044
Bibliothèque responsable: WPRO
ABSTRACT
The purpose of this study was to investigate the antimicrobial activity of the ethanol extract of Garcinia mangostana L. (mangosteen) against Cutibacterium acnes (6 strains) and Staphylococcus aureus (6 strains). The antimicrobial activity of the mangosteen extract was evaluated based on its minimal bactericidal concentration. Cytotoxicity of the mangosteen extract against human embryonic kidney 293 (HEK 293) cells was determined using the cell counting method. The data showed that the mangosteen extract was not toxic to HEK 293 cells at a concentration of up to 16 µg/mL and killed 87.0% and 99.9% of C. acnes and S. aureus after 10 minutes and 1 hour of treatment, respectively. These results suggest that ethanol extract of mangosteen can be used as an anti-acne agent.
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Mots clés
Texte intégral: 1 Indice: WPRIM Sujet Principal: Staphylococcus / Staphylococcus aureus / Numération cellulaire / Garcinia / Garcinia mangostana / Éthanol / Cellules HEK293 / Rein / Méthodes Limites du sujet: Humans langue: Ko Texte intégral: International Journal of Oral Biology Année: 2019 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Staphylococcus / Staphylococcus aureus / Numération cellulaire / Garcinia / Garcinia mangostana / Éthanol / Cellules HEK293 / Rein / Méthodes Limites du sujet: Humans langue: Ko Texte intégral: International Journal of Oral Biology Année: 2019 Type: Article