Survival Analysis of 148 Patients with Primary Diffuse Large B Cell Lymphoma / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 61-66, 2019.
Article
de Zh
| WPRIM
| ID: wpr-774358
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the clinical outcome of the patients with primary diffuse large B-cell lymphoma(DLBCL).@*METHODS@#Clinical data of 148 patients with DLBCL in our hospital and cancer hospital from March 2006 to April 2016 were retrospectively analyzed. Kaplan-Meier analysis was used to estimate progression-free survival(PFS)and overall survival(OS).@*RESULTS@#5-year OS and PFS rates were 85% and 69%,respectively. The survival analysis showed that 5-year OS rate of R-CHOP group was significantly higher than that of CHOP alone group(89% vs. 70%,P60 years),poor ECOG score(≥2),advanced stage(Ⅲ-Ⅳ),higher IPI score(≥3),CHOP alone and absence of radiotherapy related with poor survival rate. Furthermore,multivariate analysis showed that age>60 year significantly related with the worse OS.@*CONCLUSION@#Age >60 year is an important independent prognostic factor to predict worse OS or PFS.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pronostic
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Protocoles de polychimiothérapie antinéoplasique
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Doxorubicine
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Études rétrospectives
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Lymphome B diffus à grandes cellules
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Survie sans rechute
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Cyclophosphamide
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Anticorps monoclonaux d'origine murine
Type d'étude:
Observational_studies
/
Prognostic_studies
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Journal of Experimental Hematology
Année:
2019
Type:
Article