Analysis of hematological phenotype and genotype of Hb Q-Thailand in Fujian area / 中华医学遗传学杂志

ABSTRACT

OBJECTIVE@#To explore the hematological phenotype and genotype of hemoglobin Q-Thailand in Fujian area.@*METHODS@#Genomic DNA was extracted from peripheral venous blood samples of patients. Suspected samples were screened by hematological parameters analysis and verified with DNA sequencing.@*RESULTS@#In 35 patients suspected with Hb Q-Thailand, 20 were confirmed, which included one case compounded with heterozygous β mutation and one compounded with Hb New York.@*CONCLUSION@#Analysis of hematological phenotype and genotype of Hb Q-Thailand can faciliate genetic counseling for patients from Fujian area.