Super-Resolution Track-Density Imaging Reveals Fine Anatomical Features in Tree Shrew Primary Visual Cortex and Hippocampus / 神经科学通报·英文版
Neuroscience Bulletin
; (6): 438-448, 2018.
Article
de En
| WPRIM
| ID: wpr-777052
Bibliothèque responsable:
WPRO
ABSTRACT
Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to study white and gray matter (GM) micro-organization and structural connectivity in the brain. Super-resolution track-density imaging (TDI) is an image reconstruction method for dMRI data, which is capable of providing spatial resolution beyond the acquired data, as well as novel and meaningful anatomical contrast that cannot be obtained with conventional reconstruction methods. TDI has been used to reveal anatomical features in human and animal brains. In this study, we used short track TDI (stTDI), a variation of TDI with enhanced contrast for GM structures, to reconstruct direction-encoded color maps of fixed tree shrew brain. The results were compared with those obtained with the traditional diffusion tensor imaging (DTI) method. We demonstrated that fine microstructures in the tree shrew brain, such as Baillarger bands in the primary visual cortex and the longitudinal component of the mossy fibers within the hippocampal CA3 subfield, were observable with stTDI, but not with DTI reconstructions from the same dMRI data. The possible mechanisms underlying the enhanced GM contrast are discussed.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Tupaiidae
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Cortex visuel
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Traitement d'image par ordinateur
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Cartographie cérébrale
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Imagerie diagnostique
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Imagerie par tenseur de diffusion
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Hippocampe
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Méthodes
/
Voies nerveuses
Type d'étude:
Diagnostic_studies
Limites du sujet:
Animals
langue:
En
Texte intégral:
Neuroscience Bulletin
Année:
2018
Type:
Article