Transmission of Seasonal Outbreak of Childhood Enteroviral Aseptic Meningitis and Hand-foot-mouth Disease
Journal of Korean Medical Science
; : 677-683, 2010.
Article
Dans En
| WPRIM
| ID: wpr-77813
Responsable en Bibliothèque :
WPRO
ABSTRACT
This study was conducted to evaluate the modes of transmission of aseptic meningitis (AM) and hand-foot-mouth disease (HFMD) using a case-control and a case-crossover design. We recruited 205 childhood AM and 116 HFMD cases and 170 non-enteroviral disease controls from three general hospitals in Gyeongju, Pohang, and Seoul between May and August in both 2002 and 2003. For the case-crossover design, we established the hazard and non-hazard periods as week one and week four before admission, respectively. In the case-control design, drinking water that had not been boiled, not using a water purifier, changes in water quality, and contact with AM patients were significantly associated with the risk of AM (odds ratio [OR]=2.8, 2.9, 4.6, and 10.9, respectively), while drinking water that had not been boiled, having a non-water closet toilet, changes in water quality, and contact with HFMD patients were associated with risk of HFMD (OR=3.3, 2.8, 6.9, and 5.0, respectively). In the case-crossover design, many life-style variables such as contact with AM or HFMD patients, visiting a hospital, changes in water quality, presence of a skin wound, eating out, and going shopping were significantly associated with the risk of AM (OR=18.0, 7.0, 8.0, 2.2, 22.3, and 3.0, respectively) and HFMD (OR=9.0, 37.0, 11.0, 12.0, 37.0, and 5.0, respectively). Our findings suggest that person-to-person contact and contaminated water could be the principal modes of transmission of AM and HFMD.
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Indice:
WPRIM
Sujet Principal:
Saisons
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Comorbidité
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Incidence
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Épidémies de maladies
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Facteurs de risque
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Appréciation des risques
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Infections à entérovirus
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Syndrome mains-pieds-bouche
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Méningite aseptique
Type d'étude:
Etiology_studies
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Incidence_studies
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Prognostic_studies
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Risk_factors_studies
Limites du sujet:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
langue:
En
Texte intégral:
Journal of Korean Medical Science
Année:
2010
Type:
Article