A Case of Therapy-Related Acute Monocytic Leukemia following Low-dose of Etoposide Treatment for Hemophagocytic Lymphohistiocytosis / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 244-247, 2007.
Article
Dans Ko
| WPRIM
| ID: wpr-7858
Responsable en Bibliothèque :
WPRO
ABSTRACT
We report a case of therapy-related acute myeloid leukemia after low-dosed topoisomerase II inhibitor (etoposide) treatment for hemophagocytic lymphohistiocytosis (HLH). A 62-yr-old female patient had previously been treated with a HLH-94 protocol containing a low-dose of etoposide (total dose of 300 mg/m2). Thirty-one months later, the patient was admitted to the hematology department with general weakness and upper respiratory infection symptoms. Peripheral blood smear and bone marrow study revealed acute monocytic leukemia. There was no evidence of myelodysplastic syndrome, and a cytogenetic study showed no chromosomal abnormalities.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Moelle osseuse
/
Leucémie aigüe monoblastique
/
Lymphohistiocytose hémophagocytaire
/
Étoposide
Type d'étude:
Guideline
Limites du sujet:
Female
/
Humans
langue:
Ko
Texte intégral:
The Korean Journal of Laboratory Medicine
Année:
2007
Type:
Article