Massive Fetomaternal Hemorrhage Diagnosed with High-performance Liquid Chromatography / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
; : 158-161, 2016.
Article
Dans En
| WPRIM
| ID: wpr-788581
Responsable en Bibliothèque :
WPRO
ABSTRACT
Massive fetomaternal hemorrhage (FMH) is a major cause of unexplained fetal death and neonatal anemia. FMH can be diagnosed using the Kleihauer-Betke test or flow cytometry by identifying the presence of fetal red cells in the maternal blood. However, timely diagnosis is a challenge because many hospitals lack the equipment needed to perform such tests. The authors experienced a case of FMH diagnosed via high-performance liquid chromatography (HPLC) which is generally used in measuring glycated hemoglobin (HbA1c) in a patient with unexplained neonatal anemia. A girl aged 2 days was transferred to our hospital for showing pallor and a hemoglobin level of 5.0 g/dL. HPLC revealed 3% fetal hemoglobin (HbF) in the maternal blood. HPLC is a quick test for quantifying HbF that is readily available in many hospitals and could serve as a promising alternative for diagnosing FMH.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pâleur
/
Temps de prothrombine
/
Hémoglobine foetale
/
Hémoglobine glyquée
/
Chromatographie en phase liquide à haute performance
/
Chromatographie en phase liquide
/
Diagnostic
/
Mort foetale
/
Transfusion foetomaternelle
/
Cytométrie en flux
Type d'étude:
Diagnostic_studies
Limites du sujet:
Female
/
Humans
/
Newborn
/
Pregnancy
langue:
En
Texte intégral:
Clinical Pediatric Hematology-Oncology
Année:
2016
Type:
Article