Research progress of drug-loading gold nanoparticles / 药学实践杂志

ABSTRACT

In recent years ,as a novel drug delivery system ,gold nanoparticles have attracted widespread attention .Be-cause of their special physicochemical properties ,such as quantum size effect ,unique optical phenomenon ,easily reacting with thiol compounds or disulfides and so on ,gold nanoparticles can delivery variety of types of drugs ,like proteins ,nucleic acid , small molecular drugs ,therefore they can be applied in tumor treatment and detection .In this paper the preparation of drug-loading gold nanoparticles ,their drug-loading ways and safety issues were reviewed .