Laparoscopic cholecystectomy with or without percutaneous transhepatic gallbladder drainage for acute severe cholecystitis: a meta-analysis / 中华肝胆外科杂志

ABSTRACT

Objective@#To compare laparoscopic cholecystectomy (LC) with or without percutaneous transhepatic gallbladder drainage (PTGD) for acute severe cholecystitis.@*Methods@#According to the predefined inclusion and exclusion criteria, 23 articles were selected for this meta-analysis. All patients were treated with LC with or without PTGD. A meta-analysis was used to analyze the clinical efficacy.@*Results@#Compared with LC, all the surgical indicators of LC with PTGD were significantly better than LC alone (all P≤0.05), including the operation time 95%CI(-27.24, -9.27); intraoperative blood loss 95%CI(-50.25, -40.19); postoperative hospital stay 95%CI(-3.63, -0.64); rates of conversion to open abdomen OR=0.48, 95%CI(0.32, 0.74); rates of incision infection OR=0.49, 95%CI(0.25, 0.99); drainage tube indwelling time 95%CI(-2.07, -1.19); gastrointestinal function recovery time 95%CI(-1.73, -0.77); rates of bile leakage OR=0.23, 95%CI(0.12, 0.44); and rates of complications OR=0.36, 95%CI(0.27, 0.48).@*Conclusion@#Compared with LC alone, PTGD+ LC is the preferred treatment for acute severe cholecystitis.