Clinicopathological analysis of 98 cases of benign lymphoidenosis of oral mucosa / 中华口腔医学杂志

ABSTRACT

Objective@#To investigate the clinical manifestations and pathological changes of benign lymphoadenosis of oral mucosa.@*Methods@#The clinical data of 98 cases of benign lymphoadenosis of oral mucosa were analyzed.@*Results@#The clinical manifestations of benign lymphoadenosis of oral mucosa included erosive ulcer (64%) and nodule (9%) and the rate of misdiagnosis was 98%. Neutrophil infiltration occurred in the epithelium of 51% cases and the lymphocyte was diffusely infiltrated in lamina propria of 83% cases.@*Conclusions@#When the mucous membrane of the lamina propria is characterized by complex cell components, diffuse infiltrating lymphocytes and infiltration of neutrophils in mucosal epithelium without erosion and ulceration, it is necessary to highly suspect benign lymphoadenosis of oral mucosa. Finding the focal aggregation of lymphoid follicles or lymphocytes is helpful for the correct diagnosis.