Adenoid Basal Carcinoma of the Uterine Cervix
Korean Journal of Pathology
; : 351-353, 2001.
Article
de Ko
| WPRIM
| ID: wpr-80850
Bibliothèque responsable:
WPRO
ABSTRACT
We report a case of adenoid basal carcinoma of the uterine cervix unexpectedly found in a 68-year-old female. She was diagnosed with a high-grade squamous intraepithelial lesion (HSIL) on a cervical smear and subsequent cervical punch biopsy. Total abdominal hysterectomy was performed, and there were no significant gross findings in the uterine cervix. Microscopically, the epithelial surface showed a HSIL with glandular extension. Below the neoplastic epithelial lesion were numerous small nests of uniform small cells, which extended to the parametrium. These tumor cells contained hyperchromatic nuclei, inconspicuous nucleoli, and scant cytoplasm. Peripheral palisading and gland-like or acinar structures in the nests were noted. The latter were positive for mucicarmine stain. Foci of squamous differentiation exhibiting occasional mitoses and large atypical cells were seen in the small nests. Stromal reaction was not obvious. Immunohistochemically, the HSIL lesion and adenoid basal carcinoma lesion were negative for human papillowa virus. The tumor cells forming nests were positive for carcinoembryonic antigen, S-100 protein, and high molecular weight cytokeratin, but were negative for -smooth muscle actin and chromogranin A.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Frottis vaginaux
/
Biopsie
/
Antigène carcinoembryonnaire
/
Tonsilles pharyngiennes
/
Protéines S100
/
Col de l'utérus
/
Actines
/
Cytoplasme
/
Chromogranine A
/
Hystérectomie
Limites du sujet:
Aged
/
Female
/
Humans
langue:
Ko
Texte intégral:
Korean Journal of Pathology
Année:
2001
Type:
Article