Research progress in AMP-activated protein kinase and sepsis-induced cardiac dysfunction / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1364-1368, 2018.
Article
de Zh
| WPRIM
| ID: wpr-813125
Bibliothèque responsable:
WPRO
ABSTRACT
Sepsis-induced cardiac dysfunction is a serious complication of sepsis with no effective treatment. AMP-activated protein kinase (AMPK) is a regulator for energy metabolism in cells and plays a key role in the energy balance. Recent studies have shown that AMPK exerted a protective effect on sepsis-induced cardiac dysfunction, which was related to the regulation of inflammation, endothelial cells injury, energy metabolism, myocardial cells apoptosis and autophagy. Therefore, AMPK is a therapeutic target for sepsis-induced cardiac dysfunction.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Autophagie
/
Apoptose
/
Sepsie
/
AMP-Activated Protein Kinases
/
Cardiopathies
/
Métabolisme
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2018
Type:
Article