Changes and Relationship Analysis of Ocular Parameters After Short-term Discontinuation of Orthokeratology / 中山大学学报(医学科学版)

ABSTRACT

@#【Objective】To observe and assess the changes of refraction error，axial length，anterior chamber depth， intraocular pressure，and corneal topography parameters 1 month after discontinuation of orthokeratology，and analyse the related factors of refraction error growth. 【Methods】 This was a retrospective self-control clinical study ． A total of 66 children（66 eyes）with a history of wearing orthokeratology lens and voluntary discontinuation，aged 8 to 15 years，were enrolled in this study. They had worn orthokeratology lens for about 1 year，averaged 13（S = 3）months，with about 1 month of discontinuation ，averaged 29（S = 4）days. Observation of refraction error ，axial length ，anterior chamber depth ， intraocular pressure，and corneal topography parameters were taken before wearing orthokeratology lens and 1 month after discontinuation，and the changes and correlation were analyzed by paired t test and linear regression analyses.【Results】 Compared with the values at baseline，spherical equivalent refraction error and cylindrical degree increased［-0.13（-0.50~0.00）］D and［0.00（-0.25~0.00）］D，（P = 0.113）after 1 month of discontinuation，respectively. The value of steep Keratometry，and that of flat K，Em and Es both decreased 了 0.10（- 0.10~0.30）D，0.20（0.00~0.48）D，- 0.10（- 0.30~0.20）D，（P1 = 0.001，P2 < 0.001，P3 = 0.015）. Significantly，change of refraction error was only strongly correlated with axial elongation（X），and we built a predictive model for growth of refraction error（Y）：＾y = -1.294X+0.095（P < 0.001）.【Conclusion】 Refractive error exceed to baseline values completely ，and corneal power rebounded to baseline values basically after 1 month of discontinuation in children who wore orthokeratology lens for about 1 year.