Association of hypoxic microenvironment with the development and progression of liver diseases / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 1891-1895, 2020.
Article
Dans Zh
| WPRIM
| ID: wpr-825052
Responsable en Bibliothèque :
WPRO
ABSTRACT
Hypoxic microenvironment is a common phenomenon of liver diseases and runs through the whole process of the development and progression of liver diseases. In recent years, the research on liver fibrosis and hypoxic microenvironment of hepatocellular carcinoma has attracted more and more attention. Hypoxia-inducible factor (HIF) is the most important hypoxic stress factor found at present. This article reviews the characteristics of hypoxic microenvironment in the liver and liver diseases and further elaborates on the association of HIF overexpression with hepatocyte damage, formation of fibrosis, and malignant transformation of hepatocytes.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Clinical Hepatology
Année:
2020
Type:
Article