Recent progress of positron radionuclide labeled small molecule inhibitors of prostate specific membrane antigen for PET/CT imaging of prostate cancer / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 219-224, 2020.
Article
de Zh
| WPRIM
| ID: wpr-828177
Bibliothèque responsable:
WPRO
ABSTRACT
Prostate cancer is the most common tumor of the urinary system, and its mortality rate is second only to lung cancer. With the specific and high expression on the surface of prostate cancer cells, prostate-specific membrane antigen (PSMA) has been an ideal theranostic target of prostate cancer with great clinical significance and research value. Positron emission tomography/computed tomography (PET/CT), a new modality of molecular imaging combining functional metabolic information and anatomical structure, provides high diagnostic performance for cancer detection. This paper mainly reviewed recent progress of PSMA inhibitors labeled by positron-emitting radionuclides for early diagnosis, preoperative staging, response assessment, restaging and metastasis detection of prostate cancer.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Tumeurs de la prostate
/
Radio-isotopes
/
Imagerie diagnostique
/
Kallicréines
/
Chimie
/
Antigène spécifique de la prostate
/
Électrons
/
Tomographie par émission de positons couplée à la tomodensitométrie
Type d'étude:
Diagnostic_studies
/
Screening_studies
Limites du sujet:
Humans
/
Male
langue:
Zh
Texte intégral:
Journal of Biomedical Engineering
Année:
2020
Type:
Article