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Value of sTREM-1 in serum and bronchoalveolar lavage fluid, APACHE II score, and SOFA score in evaluating the conditions and prognosis of children with severe pneumonia / 中国当代儿科杂志
Zhongguo dangdai erke zazhi ; Zhongguo dangdai erke zazhi;(12): 626-631, 2020.
Article de Zh | WPRIM | ID: wpr-828695
Bibliothèque responsable: WPRO
ABSTRACT
OBJECTIVE@#To study the significance of the level of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in serum and bronchoalveolar lavage fluid (BALF), Acute Physiology and Chronic Health Evaluation II (APACHE II) score, and Sequential Organ Failure Assessment (SOFA) score in evaluating the conditions and prognosis of children with severe pneumonia.@*METHODS@#A total of 76 children with severe pneumonia who were admitted from August 2017 to October 2019 were enrolled as the severe pneumonia group. According to the treatment outcome, they were divided into a non-response group with 34 children and a response group with 42 children. Ninety-four children with common pneumonia who were admitted during the same period of time were enrolled as the common pneumonia group. One hundred healthy children who underwent physical examination in the outpatient service during the same period of time were enrolled as the control group. The serum level of sTREM-1, APACHE II score, and SOFA score were measured for each group, and the level of sTREM-1 in BALF was measured for children with severe pneumonia. The correlation of the above indices with the severity and prognosis of severe pneumonia in children was analyzed.@*RESULTS@#The severe pneumonia group had significantly higher serum sTREM-1 level, APACHEII score, and SOFA score than the common pneumonia group and the control group (P0.05).@*CONCLUSIONS@#The level of sTREM-1 in serum and BALF and SOFA score can be used to evaluate the severity and prognosis of severe pneumonia in children.
Sujet(s)
Texte intégral: 1 Indice: WPRIM Sujet Principal: Pneumopathie infectieuse / Pronostic / Liquide de lavage bronchoalvéolaire / Courbe ROC / Sepsie / Indice APACHE / Scores de dysfonction d'organes / Récepteur de déclenchement de type-1 exprimé sur les cellules myéloïdes Type d'étude: Prognostic_studies Limites du sujet: Child / Humans langue: Zh Texte intégral: Zhongguo dangdai erke zazhi Année: 2020 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Pneumopathie infectieuse / Pronostic / Liquide de lavage bronchoalvéolaire / Courbe ROC / Sepsie / Indice APACHE / Scores de dysfonction d'organes / Récepteur de déclenchement de type-1 exprimé sur les cellules myéloïdes Type d'étude: Prognostic_studies Limites du sujet: Child / Humans langue: Zh Texte intégral: Zhongguo dangdai erke zazhi Année: 2020 Type: Article