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Can Habitual Exercise Help Reduce Serum Concentrations of Lipophilic Chemical Mixtures? Association between Physical Activity and Persistent Organic Pollutants
Article de En | WPRIM | ID: wpr-832377
Bibliothèque responsable: WPRO
ABSTRACT
BackgroundLow-dose persistent organic pollutants (POPs), especially organochlorine pesticides (OCPs), have emerged as a new risk factor of many chronic diseases. As serum concentrations of POPs in humans are mainly determined by both their release from adipose tissue to circulation and their elimination from circulation, management of these internal pathways may be important in controlling the serum concentrations of POPs. As habitual physical activity can increase the elimination of POPs from circulation, we evaluated whether chronic physical activity is related to low serum POP concentrations.MethodsA cross-sectional study of 1,850 healthy adults (age ≥20 years) without cardio-metabolic diseases who participated in the U.S. National Health and Nutrition Examination Survey 1999 to 2004 was conducted. Information on moderate or vigorous leisure-time physical activity was obtained based on questionnaires. Serum concentrations of OCPs and polychlorinated biphenyls were investigated as typical POPs.ResultsSerum concentrations of OCPs among physically active subjects were significantly lower than those among physically inactive subjects (312.8 ng/g lipid vs. 538.0 ng/g lipid, PPquadratic ConclusionPhysical activity may assist in decreasing serum concentrations of lipophilic chemical mixtures such as OCPs.
Texte intégral: 1 Indice: WPRIM Type d'étude: Observational_studies / Risk_factors_studies langue: En Texte intégral: Diabetes & Metabolism Journal Année: 2020 Type: Article
Texte intégral: 1 Indice: WPRIM Type d'étude: Observational_studies / Risk_factors_studies langue: En Texte intégral: Diabetes & Metabolism Journal Année: 2020 Type: Article