Umbilical Artery Doppler Study as a Predictive Marker of Perinatal Outcome in Preterm Small for Gestational Age Infants
Yonsei Medical Journal
; : 39-44, 2009.
Article
Dans En
| WPRIM
| ID: wpr-83534
Responsable en Bibliothèque :
WPRO
ABSTRACT
PURPOSE:
To evaluate the merit of umbilical artery Doppler study as a predictive marker of perinatal outcome in preterm small for gestational age (SGA) infants. MATERIALS ANDMETHODS:
A total of 218 patients at 27 - 36 weeks of gestational age (GA) who received antenatal umbilical artery Doppler velocimetry and delivered singleton infants with SGA. The ratio of peak-systolic to end-diastolic blood flow velocities (S/D) in the umbilical artery was measured in each patient. The patients were divided into 3 groups the normal group with S/D ratios of less than 95th percentile (n = 134), elevated S/D ratio group of 95th or more percentile (n = 41), and those with absent/reversed end diastolic flow (n = 43). Maternal characteristics and neonatal outcomes of these groups were comparatively analyzed.RESULTS:
The gestational age (GA) at the time of diagnosis of SGA, the mean GA at delivery, and the mean birth weight showed statistically significant difference among three groups (p < 0.001). Also, poor perinatal outcome was significantly increased in infants with abnormal S/D ratio (13.4% vs. 31.7% vs. 67.4%, p < 0.001). Multivariate logistic regression analysis revealed umbilical artery Doppler study as a significant independent factor for prediction of poor perinatal outcome (odds ratio 3.7, 95% confidence interval 1.4 - 9.5, p = 0.007).CONCLUSION:
Antenatal umbilical artery Doppler velocimetry is shown as a significantly efficient marker in predicting perinatal outcome in preterm SGA infants.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Artères ombilicales
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Vitesse du flux sanguin
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Nourrisson petit pour son âge gestationnel
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Issue de la grossesse
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Analyse multifactorielle
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Valeur prédictive des tests
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Études rétrospectives
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Échographie prénatale
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Échographie-doppler
Type d'étude:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Limites du sujet:
Female
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Humans
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Newborn
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Pregnancy
langue:
En
Texte intégral:
Yonsei Medical Journal
Année:
2009
Type:
Article