Chemical constituents from rhizomes of Curcuma longa / 中草药

ABSTRACT

Objective: To study the chemical constituents in the rhizomes of Curcuma longa. Methods: A variety of silica gel column chromatography, Sephadex LH-20 gel column chromatography, and HPLC methods were used for the separation and purification of chemical composition. Their structures were established on the basis of physicochemical property and spectral data. Results: Thirteen compounds were obtained and identified as 5-hydroxyl-bisabolon-9-one (1), cyclocurcumin (2), demethoxyl cyclocurcumin (3), isodemethoxyl cyclocurcumin (4), curcumin (5), demethoxyl curcumin (6), methyl ferulate (7), vanillin (8), 4-hydroxyl benzoic aldehyde (9), 4-(4-hydroxyl phenyl)-2-butanone (10), 4-(4-hydroxyl-3-methoxyl phenyl)-2-butanone (11), 4-(4-hydroxyl phenyl)-3- buten-2-one (12), and 4-(4-hydroxyl-3-methoxyl phenyl)-3-buten-2-one (13). Conclusion: Compound 1 is obtained as a new compound named 5-hydroxyl-bisabolon-9-one without reported in literature until now and compound 4 is first isolated from this plant.