Research progress of synthesis and pharmacological activity of pyrazolo3, 4-d pyrimidine derivatives / 中国药学杂志

ABSTRACT

Due to the extensive pharmacological effects, pyrazolo[3, 4-d] pyrimidine derivatives have aroused great attention. There are a variety of ways in their synthesis, including using pyrazole ring, pyrimidine ring and other materials as parent ring. The compounds have strong bactericidal, anti-inflammatory, anti-cancer and anti-virus activities, etc. In this paper, the synthesis and pharmacological activities of pyrazolo[3, 4-d] pyrimidine derivatives taking the synthesis as the main line are summarized.