Evidence-based pharmacy evaluation of Ruyi Jinhuang Powder for treating phlebitis / 中国药学杂志

ABSTRACT

OBJECTIVE: To evaluate the therapeutic effect and safety of Ruyi Jinhuang Powder for phlebitis. METHODS: The Cochrane Library, PubMed database, Embase database, ISI database, CBM database, CNKI database, VIP Database, and Wanfang database were searched. Randomized controlled trials (RCT), systematic reviews (SR)and meta-analysis of treating phlebitis by Ruyi Jinhuang Powder and 50% magnesium sulfate were included. Methodological quality assessment and meta-analysis of randomized controlled trials were carried out, and the conclusions of the included systematic reviews and meta-analyses were referred to. RESULTS: Ten RCTs comparing Ruyi Jinhuang Powder and 50% magnesium sulfate for treatment of phlebitis were included into the analysis. The total efficiencies of the two drugs had statistical significance [RR 12.96, 95% CI (5.81, 28.89), P 0.05]. CONCLUSION: Ruyi Jinhuang Powder is effective for treating phlebitis, the therapeutic effect is better than 50% magnesium sulfate, and no adverse drug reaction has been reported.