Recovery of Delayed Graft Function after Calcineurin Inhibitor Sparing Regimen in a Renal Transplant Patient with Calcineurin Inhibitor Toxicity: A Case Report / 대한이식학회지
The Journal of the Korean Society for Transplantation
; : 165-168, 2014.
Article
Dans En
| WPRIM
| ID: wpr-86704
Responsable en Bibliothèque :
WPRO
ABSTRACT
The recipient candidate was a 51-year-old male with end-stage renal disease owing to diabetes mellitus. The initial immunosuppressive regimen included basiliximab for induction and tacrolimus, mycophenolate mofetil, and steroids. Urine output was 413 mL/day on the operative day and 100 mL/day on the postoperative day (POD) 1. There was no definite stenosis of the ureter or vessels. He had anuria on POD 2~4 and he had undergone hemodialysis. His serum creatinine level did not decrease. Therefore, a graft biopsy was performed on POD 4. The pathologic finding was consistent with acute calcineurin inhibitor (CNI) toxicity. There was no evidence of rejection or acute tubular necrosis. Anuria continued on POD 6; therefore, we started sirolimus instead of a CNI based regimen. Graft function was gradually recovered 1 day after reduction of CNI dose and hemodialysis was stopped. The serum creatinine level was normalized on POD 10. He was discharged on POD 21.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Anurie
/
Stéroïdes
/
Uretère
/
Biopsie
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Dialyse rénale
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Transplantation rénale
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Tacrolimus
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Sténose pathologique
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Calcineurine
/
Transplants
Limites du sujet:
Humans
/
Male
langue:
En
Texte intégral:
The Journal of the Korean Society for Transplantation
Année:
2014
Type:
Article