SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation
Acta Pharmaceutica Sinica B
; (6): 1261-1273, 2021.
Article
de En
| WPRIM
| ID: wpr-881197
Bibliothèque responsable:
WPRO
ABSTRACT
Neointimal hyperplasia after vascular injury is a representative complication of restenosis. Endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) is involved in the pathogenesis of vascular intimal hyperplasia. PARP16, a member of the poly(ADP-ribose) polymerases family, is correlated with the nuclear envelope and the ER. Here, we found that PERK and IRE1
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Indice:
WPRIM
langue:
En
Texte intégral:
Acta Pharmaceutica Sinica B
Année:
2021
Type:
Article