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Role of branched-chain amino acids in the development and progression of nonalcoholic fatty liver disease / 临床肝胆病杂志
Journal of Clinical Hepatology ; (12): 439-442, 2022.
Article de Zh | WPRIM | ID: wpr-920908
Bibliothèque responsable: WPRO
ABSTRACT
Nonalcoholic fatty liver disease is a common chronic liver disease with the risk of progression to nonalcoholic hepatitis, liver fibrosis, and hepatocellular carcinoma. Nonalcoholic fatty liver disease has various pathogeneses, among which abnormal metabolism of branched-chain amino acids can induce oxidative stress, autophagy, and mitochondrial dysfunction in hepatocytes and is the most important mechanism in the development and progression of nonalcoholic fatty liver disease. This article reviews related research advances and analyzes the possible role of abnormal metabolism of branched-chain amino acids in the development and progression of nonalcoholic fatty liver disease, in order to improve clinical awareness and diagnosis.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Journal of Clinical Hepatology Année: 2022 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Journal of Clinical Hepatology Année: 2022 Type: Article