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The evolving progress of mitochondrial oxidative stress in the pathological mechanisms of diabetic microvascular complications / 中华内分泌代谢杂志
Article de Zh | WPRIM | ID: wpr-957595
Bibliothèque responsable: WPRO
ABSTRACT
Diabetes complications are the primary cause of disability and mortality in diabetic patients. As the center of cell energy metabolism, mitochondria dysfunction is closely related to the occurrence and development of various microvascular complications. This review focuses on common complications, including diabetic ulcers, diabetic nephropathy and diabetic retinopathy, and on the research progress of mitochondrial function and oxidative stress involving pathological mechanisms of diabetic microvascular complications. We also conclude and update the theoretical basis for targeting mitochondrial oxidative stress in the treatment of these diseases.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Journal of Endocrinology and Metabolism Année: 2022 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Journal of Endocrinology and Metabolism Année: 2022 Type: Article