Association between Respiratory Disorders and Candidate Genes in Korean Newborn Infants
Neonatal Medicine
; : 311-317, 2013.
Article
de Ko
| WPRIM
| ID: wpr-97615
Bibliothèque responsable:
WPRO
ABSTRACT
Respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) remain major acute and chronic postnatal lung diseases in the Neonatal Intensive Care Unit. RDS and BPD are multifactorial diseases influenced by genetic factors. Specific genetic variants contributing to the regulation of pulmonary development, structure and function or inflammatory response, and host defense mechanism can be risk factors for the development of RDS and/or BPD. This review summarizes recent association studies of genetic polymorphisms with RDS and BPD. In addition, we analyze the genetic differences among various study populations to identify potential candidate genes for susceptibility to RDS and BPD in Korean preterm infants.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Polymorphisme génétique
/
Dysplasie bronchopulmonaire
/
Prématuré
/
Soins intensifs néonatals
/
Facteurs de risque
/
Maladies pulmonaires
Type d'étude:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Humans
/
Newborn
langue:
Ko
Texte intégral:
Neonatal Medicine
Année:
2013
Type:
Article