Research of progress of mitochondria in the pathogenesis of sepsis / 中华危重病急救医学
Chinese Critical Care Medicine
; (12): 669-672, 2023.
Article
de Zh
| WPRIM
| ID: wpr-982652
Bibliothèque responsable:
WPRO
ABSTRACT
Sepsis is an organ dysfunction caused by dysregulation of the body's response to infection, with high morbidity and mortality. The pathogenesis of sepsis is still unclear, and there are no specific treatment drugs. As a cell energy supply unit, the dynamic changes of mitochondria are closely related to various diseases. Studies have shown that structure and function of mitochondria are changed in different organs during sepsis. The energy shortage, oxidative stress change, imbalance of fusion and fission, autophagy reduce, biological functions of mitochondria play important roles in sepsis progress, which can provide a research target for the treatment of sepsis.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Autophagie
/
Sepsie
/
Stress oxydatif
/
Mitochondries
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Chinese Critical Care Medicine
Année:
2023
Type:
Article