Gastric Adenocarcinoma with Coexistent Hepatoid Adenocarcinoma and Neuroendocrine Carcinoma: A Case Report
Korean Journal of Pathology
; : 79-82, 2009.
Article
Dans En
| WPRIM
| ID: wpr-9836
Responsable en Bibliothèque :
WPRO
ABSTRACT
This report represents a very rare case of a gastric adenocarcinoma that was coexistent with hepatoid adenocarcinoma and neuroendocrine carcinoma. A 77-year-old man was admitted to our hospital due to a huge ulcerofungating mass identified at the proximal body of the stomach. After a pathological diagnosis of the tumor as a poorly differentiated adenocarcinoma was made, the patient underwent a total gastrectomy with lymph node dissection. Microscopically, the tumor consisted of three morphologically distinct components-tubular adenocarcinoma, hepatoid adenocarcinoma and neuroendocrine carcinoma. The hepatoid adenocarcinoma component resembled a hepatocellular carcinoma and produced alpha-fetoprotein. The neuroendocrine carcinoma component was positive for chromogranin and synaptophysin immunostains. This is an example of the diverse morphological and immunophenotypical differentiation of gastric carcinomas.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Estomac
/
Tumeurs de l'estomac
/
Adénocarcinome
/
Alphafoetoprotéines
/
Synaptophysine
/
Carcinome neuroendocrine
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Carcinome hépatocellulaire
/
Gastrectomie
/
Lymphadénectomie
Limites du sujet:
Aged
/
Humans
langue:
En
Texte intégral:
Korean Journal of Pathology
Année:
2009
Type:
Article