A Case of Vitiligo Developed on the Sites of DNCB Application in a Patient with Alopecia Areata / 대한피부과학회지
Korean Journal of Dermatology
; : 452-455, 2004.
Article
Dans Ko
| WPRIM
| ID: wpr-99987
Responsable en Bibliothèque :
WPRO
ABSTRACT
We report a case of vitiligo developed on the sites of DNCB application for the treatment of alopecia areata in a 53-year-old woman. Histopathologic studies of the depigmented patches showed absence of melanin pigmentation at the basal layer of the epidermis and a negative reaction for the Fontana-Masson stain. The current theories explaining vitiligo development after topical sensitizer application are that topical sensitizers induce the vitiligo by a direct cytotoxic effect on the melanocytes, or by unmasking latent vitiligo as a result of the Koebner phenomenon due to contact dermatitis, but the exact mechanism is still unclear.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Vitiligo
/
Pigmentation
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Eczéma de contact
/
1-Chloro-2,4-dinitro-benzène
/
Épiderme
/
Alopécie
/
Pelade
/
Mélanines
/
Mélanocytes
Limites du sujet:
Female
/
Humans
langue:
Ko
Texte intégral:
Korean Journal of Dermatology
Année:
2004
Type:
Article