Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report
Rev. Soc. Bras. Med. Trop
; 51(2): 231-233, Mar.-Apr. 2018. tab
Article
em En
| LILACS
| ID: biblio-1041452
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. METHODS In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. RESULTS Fas2-ELISA demonstrated negative results in all HCC patients included in this study. CONCLUSIONS The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.Palavras-chave
Texto completo:
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Índice:
LILACS
Assunto principal:
Imunoglobulina G
/
Anticorpos Anti-Helmínticos
/
Carcinoma Hepatocelular
/
Fasciola hepatica
/
Fasciolíase
/
Neoplasias Hepáticas
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Aged80
/
Animals
/
Female
/
Humans
/
Male
País/Região como assunto:
America do sul
/
Peru
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2018
Tipo de documento:
Article