The topical treatment of old world cutaneous leishmaniasis with gentian violet along with cryotherapy: a pilot single-blind randomized controlled clinical trial
Rev. Soc. Bras. Med. Trop
; 52: e20180278, 2019. tab, graf
Article
em En
| LILACS
| ID: biblio-1041586
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
The promising non-clinical antileishmanial effects of gentian violet (GV) encouraged us to evaluate the additive effect of GV on cryotherapy.METHODS:
For 8 weeks, 59/161 cutaneous leishmaniasis patients/lesions underwent cryotherapy alone (group 1) or cryotherapy accompanied by 1% GV application (group 2). The primary endpoint was clinical response.RESULTS:
Ultimately, 54.7% and 45.3% of the significantly cured lesions belonged to groups 1 and 2, respectively, which was not statistically significant. The clinical response was significantly different between the two groups at the end of the fourth week.CONCLUSIONS:
Although the clinical response of the two groups was significantly different at the end of the fourth week, application of GV did not increase the efficacy of cryotherapy.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Leishmaniose Cutânea
/
Crioterapia
/
Violeta Genciana
/
Anti-Infecciosos Locais
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2019
Tipo de documento:
Article