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Hyptis brevipes and Paullinia pinnata extracts and their fractions presenting activity against Mycobacterium abscessos SubSP. massiliense
Neves, Rogério Coutinho das; Andrade, Rayany Gomes; Carollo, Carlos Alexandre; Boaretto, Amanda Galdi; Kipnis, Andre; Kipnis, Ana Paula Junqueira.
Afiliação
  • Neves, Rogério Coutinho das; Universidade Federal de Goiás. Goiania. BR
  • Andrade, Rayany Gomes; Universidade Federal de Goiás. Goiania. BR
  • Carollo, Carlos Alexandre; Universidade Federal do Mato Grosso do Sul. Campo Grande. BR
  • Boaretto, Amanda Galdi; Universidade Fedral do Mato Grosso do Sul. Campo Grande. BR
  • Kipnis, Andre; Universidade Federal de Goiás. Goiania. BR
  • Kipnis, Ana Paula Junqueira; Universidade Federal de Goiás. Goiania. BR
Rev. patol. trop ; 48(3): 148-160, 2019.
Article em En | LILACS | ID: biblio-1096710
Biblioteca responsável: BR15.1
ABSTRACT
Medicinal plants are of great interest for the discovery of new biomolecules with diversified effects. Over the last decade different outbreaks caused by Mycobacterium abscessos subsp. Massiliense have been reported, evidencing it as an important emerging pathogen in underdeveloped countries. This study investigated the antimycobacterial activity of six Brazilian medicinal plant extracts and their fractions. Hyptis brevipes, Tocoyena formosa, Randia armata, Paullinia pinnata, La foensia pacari And Anadenanthera colubrina were evaluated against M. a. massiliense. Total extracts from the medicinal plants H. brevipes, T. formosa, P. pinnata and L. pacari presented a minimal bactericidal concentration of 1 mg/mL. After fractioning, the ethanolic fractions from H. brevipes and P. pinnata presented bactericidal activity, and the ethyl acetate fraction from H. brevipes and T. formosa presented antimycobacterial action. The best bactericidal function of all plant fractions was the ethanolic, which contained rutin and rosmarinic acid that were shown to have microbicidal activity.
Assuntos
Texto completo: 1 Índice: LILACS Assunto principal: Plantas Medicinais / Hyptis / Paullinia / Biodiversidade / Mycobacterium abscessus Idioma: En Revista: Rev. patol. trop Assunto da revista: MEDICINA TROPICAL / PATOLOGIA Ano de publicação: 2019 Tipo de documento: Article
Texto completo: 1 Índice: LILACS Assunto principal: Plantas Medicinais / Hyptis / Paullinia / Biodiversidade / Mycobacterium abscessus Idioma: En Revista: Rev. patol. trop Assunto da revista: MEDICINA TROPICAL / PATOLOGIA Ano de publicação: 2019 Tipo de documento: Article