Comparison of TNF-α and IL-1ß Concentrations in Gingival Crevicular Fluid During Early Alignment Stage of Orthodontic Treatment in Adults and Adolescents
Pesqui. bras. odontopediatria clín. integr
; 20: e0004, 2020. tab
Article
em En
| LILACS, BBO
| ID: biblio-1135504
Biblioteca responsável:
BR1264.1
ABSTRACT
Abstract Objective:
To compare the levels of TNF-α and IL-1β in the gingival crevicular fluid (GCF) during early leveling stage of orthodontic treatment. Material andMethods:
This study was carried out on 20 orthodontic patients, including 10 teenagers and 10 adults. Before bonding, GCF was collected with a paper strip in gingival sulcus of maxillary right central incisor on the disto labial aspect for 60 seconds, followed by bonding and insertion of initial 14 NiTi archwire. GCF collection was repeated 24 hours, 7 days, and 28 days after bonding. Measurement of TNF-α and IL-1β levels was done utilizing Enzyme-Linked Immunosorbent Assay (ELISA). Data were analyzed in SPSS using repeated measurement test.Results:
Concentration of TNF-α and IL-1β increased after treatment. There was no significant relationship between TNF-α and IL-1β concentrations subsequent to bonding in comparison to the baseline. There was no significant relationship in TNF-α and IL-1β level changes in the two age groups and between males and females.Conclusion:
Concentration of TNF-α and IL-1β increased after treatment. Age and sex had no statically significant effect on the concentration of TNF-α and IL-1β.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Ortodontia
/
Ensaio de Imunoadsorção Enzimática
/
Líquido do Sulco Gengival
/
Adolescente
/
Interleucina-1
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Pesqui. bras. odontopediatria clín. integr
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2020
Tipo de documento:
Article