Laboratory diagnosis of human T-lymphotropic virus in Brazil: assays, flowcharts, challenges, and perspectives
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;54: e01752021, 2021. tab, graf
Article
em En
| LILACS
| ID: biblio-1250822
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract INTRODUCTION We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil. METHODS Target populations, available diagnostic serological assays (screening and complementary tests), molecular assays (in-house), causes of false-positive and false-negative results, and flowcharts were analyzed. RESULTS A table presents the target populations, two diagnostic flowcharts (depending on laboratory infrastructure and study population), and recent research that may improve how HTLV-1/2 is diagnosed in Brazil. CONCLUSIONS:
Our results support the implementation of public policies to reduce HTLV-1/2 transmission and its associated diseases.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Vírus Linfotrópico T Tipo 1 Humano
/
Infecções por HTLV-I
/
Infecções por HTLV-II
/
Técnicas de Laboratório Clínico
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2021
Tipo de documento:
Article