Lymphocytic thrombophilic arteritis with lower-limb ulcers
An. bras. dermatol
; An. bras. dermatol;96(3): 315-318, May-June 2021. graf
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em En
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| ID: biblio-1285056
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BR1.1
ABSTRACT
Abstract Lymphocytic thrombophilic arteritis is a recently described entity, histopathologically characterized by lymphocytic vasculitis that affects the arterioles of the dermo-hypodermic junction, associated with deposition of fibrin and a luminal fibrin ring. A 49-year-old female patient presented with achromic maculae and a well-defined ulcer on the medial aspect of the left lower limb. The biopsy showed intense inflammatory infiltrate in the papillary dermis with a predominance of lymphocytes, and medium-caliber vessels surrounded by mononuclear infiltrates in the deep reticular dermis. Masson's trichrome staining showed intense destruction of the muscle layer of the vascular wall and a fibrin ring. Good clinical response was attained with azathioprine. The authors believe that the ulceration might be another clinical presentation or represent an atypical progression of this condition.
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Texto completo:
1
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LILACS
Assunto principal:
Arterite
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Úlcera da Perna
Limite:
Female
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Humans
Idioma:
En
Revista:
ABD: Anais brasileiros de dermatologia
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An Bras Dermatol
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An. bras. dermatol
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An. bras. dermatol. (Online)
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Anais brasileiros de dermatologia (Impresso)
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article