Prevalence of anal intraepithelial lesions in patients with inflammatory bowel disease
J. coloproctol. (Rio J., Impr.)
; 41(3): 222-227, July-Sept. 2021. tab
Article
em En
| LILACS
| ID: biblio-1346422
Biblioteca responsável:
BR545.3
ABSTRACT
Introduction:
Anal intraepithelial neoplasia (AIN) is a premalignant lesion of the anal canal associated with HPV, with a higher prevalence in immunosuppressed individuals. Patients with inflammatory bowel disease (IBD) are at potential risk for their development, due to the use of immunosuppressants and certain characteristics of the disease.Method:
This is a prospective, cross-sectional, and interventional study that included 53 patients with IBD treated at a tertiary outpatient clinic, who underwent anal smear for cytology in order to assess the prevalence of AIN and associated risk factors.Results:
Forty-eight samples were negative for dysplasia and 2 were positive (4%). Both positive samples occurred in women, with Crohn's disease (CD), who were immunosuppressed and had a history of receptive anal intercourse.Discussion:
The prevalence of anal dysplasia in IBD patients in this study is similar to that described in low-risk populations. Literature data are scarce and conflicting and there is no evidence to recommend screening with routine anal cytology in patients with IBD. Female gender, history of receptive anal intercourse, immunosuppression and CD seem to be risk factors. (AU)Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Canal Anal
/
Neoplasias do Ânus
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Doenças Inflamatórias Intestinais
Tipo de estudo:
Prevalence_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
J. coloproctol. (Rio J., Impr.)
Assunto da revista:
Cirurgia
/
Doenas Retais
/
Doenas do Colo
/
GASTROENTEROLOGIA
/
Cirurgia
Ano de publicação:
2021
Tipo de documento:
Article