Leucemia mieloide crónica atípica BCR-ABL1 negativa: reporte de 2 casos / BCR-ABL1 negative chronic myeloid leukemia: report of two cases
Rev. méd. Chile
; 150(3): 397-401, mar. 2022. ilus, tab
Article
em Es
| LILACS
| ID: biblio-1409816
Biblioteca responsável:
CL126.2
ABSTRACT
BCR-ABL1 negative atypical chronic myeloid leukemia (aCML) is a rare type of myeloproliferative / myelodysplastic syndrome characterized by leukocytosis and proliferation of dysplastic neutrophilic precursors in the absence of positivity for the BCR-ABL1 fusion gene. We report a 66-year-old woman and a 57-year-old man with aCML, who initially presented with general malaise and weight loss, associated with anemia, thrombocytopenia, and leukocytosis with left shift and dysplasia in the neutrophil series. Both evolved unfavorably after admission and died a few days later due to multiple organ failure.
Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Trombocitopenia
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Leucemia Mielogênica Crônica BCR-ABL Positiva
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Leucemia Mieloide Crônica Atípica BCR-ABL Negativa
Limite:
Aged
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Female
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Humans
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Male
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2022
Tipo de documento:
Article