Acinic cell carcinoma of the oral and maxillofacial region: an international multicenter study
Braz. oral res. (Online)
;
37: e050, 2023. tab, graf
Artigo
em Inglês
|
LILACS-Express
| LILACS, BBO
| ID: biblio-1439744
ABSTRACT
Abstract The aim of this study was to describe the prevalence, clinicopathological, and prognostic features of acinic cell carcinoma (AciCC) of the oral and maxillofacial region. AciCC cases were retrospectively retrieved from 11 pathology centers of three different countries. Medical records were examined to extract demographic, clinical, pathologic, and follow-up information. A total of 75 cases were included. Females (65.33%) with a mean age of 45.51 years were mostly affected. The lesions usually presented as an asymptomatic (64.28%) nodule (95.66%) in the parotid gland (70.68%). The association of two histopathological patterns was the most common finding (48.93%) and the tumors presented mainly conventional histopathological grades (86.11%). Surgical treatment was performed in the majority of the cases (59.19%). Local recurrence was observed in 20% of the informed cases, regional metastasis in 30.43%, and distant metastasis in 12.50%. The statistical analysis showed that the cases with a solid histopathological pattern (p=0.01), high-grade transformation (p=0.008), recurrence (p=0.007), and regional metastasis (p=0.03) were associated with poor survival. In conclusion, high histopathological transformation, presence of nodal metastasis, and recurrence were prognostic factors for AciCC of the oral and maxillofacial region.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Braz. oral res. (Online)
Assunto da revista:
Odontologia
Ano de publicação:
2023
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
/
Guatemala
/
África do Sul
/
Reino Unido
/
Uruguai
Instituição/País de afiliação:
Clinical Center of Head and Neck/GT
/
Santa Casa de Misericórdia de Porto Alegre/BR
/
Universidad de la República/UY
/
Universidade Estadual de Campinas/BR
/
Universidade Federal da Bahia/BR
/
Universidade Federal de Goias/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal de Pelotas/BR
/
Universidade Federal do Pará/BR
/
Universidade Federal do Rio Grande do Sul/BR
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