Evaluation of the effectiveness of sodium hyaluronate, sesame oil, honey, and silver nanoparticles in preventing postoperative surgical adhesion formation. An experimental study
Acta cir. bras
; 32(8): 626-632, Aug. 2017. tab, graf
Article
em En
| LILACS
| ID: biblio-886226
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To evaluate the effectiveness of sodium hyaluronate, sesame oil, honey, and silver nanoparticles in preventing of postoperative surgical adhesion formation.Methods:
Forty male Wistar rats were randomly assigned into five groups with eight rats in each group including control, hyaluronate, sesame, honey and silver groups. After two weeks the animals underwent laparotomy and were evaluated by two different blinded surgeons for severity of adhesions based on the two different classification scoring systems including Nair classification and cumulative adhesion scoring scale.Results:
The scores of severity of adhesions in the hyaluronate and sesame groups were significantly lower than the control group based on the Nair classification (both P-values = 0.02), however based on the cumulative adhesion scoring scale just the score of severity of adhesions in the hyaluronate group was significantly lower than the control group (P-value = 0.02). In the hyaluronate group the severity of adhesions was decreased by 48% based on the cumulative adhesion scoring scale.Conclusions:
Sodium hyaluronate and sesame oil may have a significant effect in preventing postoperative surgical adhesion formation.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Complicações Pós-Operatórias
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Prata
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Óleo de Gergelim
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Nanopartículas Metálicas
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Mel
/
Ácido Hialurônico
Tipo de estudo:
Evaluation_studies
Limite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2017
Tipo de documento:
Article