Effectiveness of implantation of cardioverter-defibrillators therapy in patients with non-ischemic heart failure: an updated systematic review and meta-analysis
Rev. bras. cir. cardiovasc
; 32(5): 417-422, Sept.-Oct. 2017. tab, graf
Article
em En
| LILACS
| ID: biblio-897939
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Objective:
Implantable cardioverter-defibrillator has become the first-line therapy for prevention of sudden cardiac death. Controversial results still exist regarding the effectiveness of implantable cardioverter-defibrillator (ICD) in non-ischemic heart failure.Methods:
The PubMed, Embase, and Cochrane Central databases were searched for randomized trials comparing implantable cardioverter-defibrillator in combination with medical treatment versus medical treatment for non-ischemic heart failure. The primary endpoint was incidence of all-cause death. We derived pooled risk ratios with fixed-effects models.Results:
Five studies enrolling 2573 patients were included. Compared with medical treatment, implantable cardioverter-defibrillator with medical treatment was associated with a significantly lower risk for all-cause mortality (Risk ratio 0.83; 95% confidence interval 0.71 to 0.97).Conclusion:
Compared with medical treatment only, implantable cardioverter-defibrillator in combination with medical treatment reduces all-cause mortality.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Desfibriladores Implantáveis
/
Insuficiência Cardíaca
Tipo de estudo:
Clinical_trials
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Rev. bras. cir. cardiovasc
Assunto da revista:
CARDIOLOGIA
/
CIRURGIA GERAL
Ano de publicação:
2017
Tipo de documento:
Article