Toxicological evaluation of the root and stem bark extracts of madhuca indica

ABSTRACT

This research work was conducted with the root and stem bark of Madhuca indica to find out their toxicological properties employing Brine Shrimp Lethality Bioassay. It was found that the root and stem extracts of the plant contained some constituents that were toxic for the Brine Shrimp Nauplii. The ether and alcohol extracts may have cytotoxic properties as well as other pharmacological activities but the ethyl acetate extracts showed mild activity. The results were discussed with reference to the indication of using the plant extracts as anti-mutagenic agent and appeared to be well-supported by their chemical constituents