[Effect of Phoenix Dactylifera Spathe hydroalcoholic extract on chronic pain in mice]
Journal of Medicinal Plants. 2012; 11 (42): 136-144
em Fa
| IMEMR
| ID: emr-132461
Biblioteca responsável:
EMRO
ABSTRACT
In Persian traditional medicine, many medicinal plants have been used as analgesics; in which one of them is the distillate of Phoenix Dactylifera Spathe [PDS] known as "Tarooneh". This study was conducted to assess the antinociceptive effect of Tarooneh [PDS] hydro alcoholic extract on inflammatory pain induced by formaline in mice. In this study, 28 male albino mice weighting 25 - 30 grams, were randomly and equally divided into 4 groups. 2, 20 and 200 mg/kg PDS extract and vehicle were administered intraperitomeally to the test and control groups respectively in a volume of 10 ml/kg. Animals were subjected to Formalin test as an animal model for inflammatory pain assessment. Mean pain score induced by formalin test in control group was 1.665 +/- 0.0599 while in test groups receiving 2, 20 and 200 mg/kg PDS extract were 1.079 +/- 0.0666, 0.9192 +/- 0.0822 and 0.3842 +/- 0.0658 respectively. data from this study revealed that PDS extract, significantly and dose dependently, attenuated the inflammatory formalin induced pain in mice
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Índice:
IMEMR
Assunto principal:
Dor
/
Plantas Medicinais
/
Extratos Vegetais
/
Dor Crônica
/
Analgésicos
/
Medicina Tradicional
/
Camundongos
Limite:
Animals
Idioma:
Fa
Revista:
J. Med. Plants
Ano de publicação:
2012