Relationship between 24-hour mean pulse pressure and the cardiac function in the elderly with isolated systolic hypertension

ABSTRACT

To investigate the effect of mean pulse pressure during 24 hours on cardiac function in the elderly with isolated systolic hypertension. One hundred seventy two elderly patients with isolated systolic hypertension were enrolled to determine mean pulse pressure by monitoring 24-hour ambulatory blood pressure and to analyze the cardiac function by nuclide cardiac blood pool imaging. Twenty four hours mean pulse pressure negatively correlated with left ventricular ejection fraction [LVEF] [r = - 0.46, P < 0.01], and also with peak filling rate [RFR] [r = - 0.41, P < 0.05]. The greater the mean pulse pressure, the worse the cardiac function [P < 0.01]. The 24-hours mean pulse pressure was an important factor predicting risk for cardiac disfunction in the elderly with isolated systolic hypertension