Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan
EMHJ-Eastern Mediterranean Health Journal. 2003; 9 (4): 844-855
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| IMEMR
| ID: emr-158221
Biblioteca responsável:
EMRO
ABSTRACT
A latex agglutination test to detect urinary antigens for visceral leishmaniasis [VL] was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all KAtex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While KAtex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test [DAT] was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results:
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Índice:
IMEMR
Assunto principal:
Parasitologia
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Leishmania donovani
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Ensaio de Imunoadsorção Enzimática
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Testes de Fixação do Látex
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Immunoblotting
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Estudos de Casos e Controles
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Pré-Escolar
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Técnica Indireta de Fluorescência para Anticorpo
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Doenças Endêmicas
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Antígenos de Protozoários
Limite:
Humans
Idioma:
En
Revista:
East Mediterr Health J.
Ano de publicação:
2003