Post mydriasis rise in intraoccular pressure with tropicamide in normal individuals, glaucoma cases with and without rapid progression
Journal of Sheikh Zayed Medical College [JSZMC]. 2015; 6 (1): 757-759
em En
| IMEMR
| ID: emr-175943
Biblioteca responsável:
EMRO
Background: Rise in intraoccular pressure [IOP] may have significant effects on optic disc
Objective: To compare postmydriasis rise in intraoccular pressure with tropicamide in normal individuals and glaucoma cases with or without rapid progression
Subjects and Methods: Study design: Quasi-experimental. Sampling Technique: Non-Randomized, consecutive sampling. This study was performed on 116 eyes of 116 patients reporting at Eye Department, Combined Military Hospital [CMH], Lahore from 1[st] August 2012 to 30[th] April 2013. They were assigned to three groups based on their glaucoma profile: Group A: Normal subjects without raised IOP or glaucomatous visual field loss. Group B: Diagnosed cases of glaucoma without significant visual field defect progression. Group C: Diagnosed cases of glaucoma with significant visual field defect progression over last two years. SPSS version 16 Software was used for statistical analysis to compare intra-ocular pressure changes postmydriasis in the three groups
Results: IOP rise post-mydriasis was low [1.89 mmhg] in normal individuals whereas the spike was statistically significant in glaucoma patients [5.88 mmHg]. Diagnosed cases of glaucoma with worst prognosis has a relatively higher IOP spike [10.6 mmhg] as compared to those with slower visual field defects [5.88 mmhg] progression.[p<0.05]
Conclusion: Our study showed a significant rise in IOP in glaucoma patients with and without rapid progression as compared to normal subjects. Post-mydriasis IOP spike is a reliable diagnostic and prognostic provocative test for glaucoma suspects and diagnosed cases. However, the negative effects of raised IOP on an already compromised optic nerve head must be kept in mind
Objective: To compare postmydriasis rise in intraoccular pressure with tropicamide in normal individuals and glaucoma cases with or without rapid progression
Subjects and Methods: Study design: Quasi-experimental. Sampling Technique: Non-Randomized, consecutive sampling. This study was performed on 116 eyes of 116 patients reporting at Eye Department, Combined Military Hospital [CMH], Lahore from 1[st] August 2012 to 30[th] April 2013. They were assigned to three groups based on their glaucoma profile: Group A: Normal subjects without raised IOP or glaucomatous visual field loss. Group B: Diagnosed cases of glaucoma without significant visual field defect progression. Group C: Diagnosed cases of glaucoma with significant visual field defect progression over last two years. SPSS version 16 Software was used for statistical analysis to compare intra-ocular pressure changes postmydriasis in the three groups
Results: IOP rise post-mydriasis was low [1.89 mmhg] in normal individuals whereas the spike was statistically significant in glaucoma patients [5.88 mmHg]. Diagnosed cases of glaucoma with worst prognosis has a relatively higher IOP spike [10.6 mmhg] as compared to those with slower visual field defects [5.88 mmhg] progression.[p<0.05]
Conclusion: Our study showed a significant rise in IOP in glaucoma patients with and without rapid progression as compared to normal subjects. Post-mydriasis IOP spike is a reliable diagnostic and prognostic provocative test for glaucoma suspects and diagnosed cases. However, the negative effects of raised IOP on an already compromised optic nerve head must be kept in mind
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Índice:
IMEMR
Tipo de estudo:
Clinical_trials
Idioma:
En
Revista:
J. Sheikh Zayed Med. Coll.
Ano de publicação:
2015