Effect of atrial extract on the ACTH and cortisol response to stress in rats
Bulletin of Alexandria Faculty of Medicine. 1997; 33 (1): 63-67
em En
| IMEMR
| ID: emr-44203
Biblioteca responsável:
EMRO
ABSTRACT
Twenty male albino rats were divided into two groups Control group [receiving intravenous placebo] and experimental group [receiving intravenous atrial extract [80 mug/kg body weight] before being subjected to stress induced by ether inhalation for 60 seconds]. Plasma ACTH, cortisol, aldosterone, glucose and sodium were estimated for all rats basally as well as 15, 30 and 45 minutes after ether inhalation. In placebo-treated rats, ether inhalation resulted in statistically significant increase in plasma ACTH and cortisol. In atrial extract-treated rats, the ACTH and cortisol responses to stress were statistically suppressed when compared with the control response. No changes in plasma aldosterone, glucose or sodium were detected
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Índice:
IMEMR
Assunto principal:
Ratos
/
Estresse Fisiológico
/
Hidrocortisona
/
Hormônio Adrenocorticotrópico
Limite:
Animals
Idioma:
En
Revista:
Bull. Alex. Fac. Med.
Ano de publicação:
1997