Comparative study of misoprostol versus dinoprostone in cervical ripening and labour induction

ABSTRACT

The aim of this study was to compare the safety and efficacy of intravaginal administered misoprostol [cytotec] versus dinoprostone pessary [prostin E2] for cervical ripening and labor induction. Sixty patients requiring induction of labor for different medical or obstetrical indications were included in this study. The misoprostol group had a significant reduction in median induction delivery time compared to dinoprostone group. There was a reduced need for the oxytocin augmentation and there was no significant difference in the mode of delivery. There were no adverse neonatal outcomes associated with the use of misoprostol. It was concluded that 100 mug vaginal misoprostol was a more effective induction agent than 3 mg dinoprostone vaginal pessary